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Article

Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.

Annals of human genetics - 1 May 2013

Naj Adam C, Scott William K, Courtenay Monique D, Cade William H, Schwartz Stephen G, Kovach Jaclyn L, Agarwal Anita, Wang Gaofeng, Haines Jonathan L, Pericak-Vance Margaret A

Abstract excerpt

Relatively little is known about the interaction between genes and environment in the complex etiology of age-related macular degeneration (AMD). This study aimed to identify novel factors associated with AMD by analyzing gene-smoking interactions in a genome-wide association study of 1207 AMD cases and 686 controls of Caucasian background with genotype data on 668,238 single nucleotide polymorphisms (SNPs) after...

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Source

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Identifiers

PMID: 23577725
DOI: 10.1111/ahg.12011
PMCID: PMC3625984

Genes

ARMS2
CDH7
CFB
CFH
SERPINB8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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