Article
Correlation between the interactions of ABCA4 polymorphisms and smoking with the susceptibility to age-related macular degeneration.
International journal of clinical and experimental pathology - 1 Jan 2015
Wu Ying, Tian Lei, Huang Yifei
Abstract excerpt
OBJECTIVE: Our study was aimed to analyze the relationship between retina-specific ATP-binding cassette, sub-family A, member 4 (ABCA4) gene polymorphisms and gene-environment interactions with age-related macular degeneration (AMD) susceptibility. METHODS: 98 AMD patients and 110 healthy controls, matched in age and sex, were enrolled in this study. ABCA4 polymorphisms (2633C>A, 5646G>A and 6389T>A) were...
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