Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration.

Human heredity - 1 Jan 2007

Francis Peter J, George Sarah, Schultz Dennis W, Rosner Bernard, Hamon Sara, Ott Jurg, Weleber Richard G, Klein Michael L, Seddon Johanna M

Abstract excerpt

BACKGROUND AND AIMS: Age-related macular degeneration (AMD) is the leading cause of blindness in the Western World. It is now evident that both genetic and environmental factors contribute to disease susceptibility. We tested the hypotheses that (a) a common coding SNP in the LOC387715 gene is associated with advanced AMD (geographic atrophy or choroidal neovascularization), and (b) that modifiable environmental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Body Mass Index

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Environment

Share to Heterozygote

Share to Macular Degeneration

Share to Proteins

Share to Smoking

Source

Identifiers

PMID: 17347568
DOI: 10.1159/000100046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The LOC387715 gene, smoking, body mass index, environmental associations with advanced age-related macular degeneration.PMID 17347568Read ↗

The LOC387715 polymorphism and age-related macular degeneration: replication in three case-control samples.Semantic proximity Read ↗

Correlation between genetic and environmental risk factors for age-related macular degeneration in Brazilian patients.Semantic proximity Read ↗

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors.Semantic proximity Read ↗

The LOC387715 polymorphism, inflammatory markers, smoking, and age-related macular degeneration. A population-based case-control study.Semantic proximity Read ↗

Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration.Semantic proximity Read ↗

Age‐related macular degeneration—clinical review and genetics updateSemantic proximity Read ↗

Phenotype analysis of patients with the risk variant LOC387715 (A69S) in age-related macular degeneration.Semantic proximity Read ↗

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.Semantic proximity Read ↗

Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.Semantic proximity Read ↗

LOC387715/HTRA1 polymorphisms, smoking and combined effects on exudative age-related macular degeneration in a Korean population.Semantic proximity Read ↗

Age-related macular degeneration: genetic and environmental factors of disease.Semantic proximity Read ↗

LOC387715, smoking and their prognostic impact on visual functional status in age-related macular degeneration-The Muenster Aging and Retina Study (MARS) cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.