HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH.

doi:10.1167/iovs.07-1520

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Article

HTRA1 variants in exudative age-related macular degeneration and interactions with smoking and CFH.

Investigative ophthalmology & visual science - 1 Jun 2008

Tam Pancy O S, Ng Tsz Kin, Liu David T L, Chan Wai Man, Chiang Sylvia W Y, Chen Li Jia, DeWan Andrew, Hoh Josephine, Lam Dennis S C, Pang Chi Pui

Abstract excerpt

PURPOSE: Mapping the genes for age-related macular degeneration (AMD) had not been successful until recent genome-wide association studies revealed Tyr402His in CFH and rs11200638 in HTRA1 as AMD-related genetic variants. This study was conducted to identify other critical factors in HTRA1 that a...

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Identifiers

PMID: 18316707
DOI: 10.1167/iovs.07-1520
PMCID: PMC3215269

Genes

HTRA1
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18316707-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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