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Air pollutants, genetic susceptibility, and the risk of age-related macular degeneration: a large prospective cohort study.

European journal of epidemiology - 1 Feb 2026

Chen Shengli, Wang Gongyue, Guan Xin, Wang Chenming, Xiao Yang, Li Xingdi, Hong Shiru, Zhou Yuhan, You Yingqian, Fu Ye, Wang Yuxi, Zhang Yichi, Zhao Hui, Zhang Yingchen, Cheng Yang, Guo Huan, Xie Huatao

Abstract excerpt

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss worldwide. However, evidence regarding the relationship between air pollution and AMD is limited, and the modifying effect of genetic susceptibility on this association remains unknown. A total of 445,237 participants without AMD at baseline were included from the UK Biobank. The concentrations of nitrogen dioxide (NO2),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41524889
DOI: 10.1007/s10654-025-01340-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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