Article
Linkage analysis of two murine polycystic kidney disease genes, pcy and cpk.
Jikken dobutsu. Experimental animals - 1 Oct 1991
Nagao S, Takahashi H
Abstract excerpt
Two murine models of polycystic kidney disease (PKD) in humans are currently available: the infant-type cpk in mice and the adult-type pcy mutation in mice. Our linkage analysis was to determine whether these genes are allelic forms of the same gene, or infant-type and adult-type PKD resulting from homozygous and heterozygous mutation, as in the rat Cy gene. We found that the pcy gene in the mice was linked with...
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