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Article

Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data.

BMC medical genetics - 6 Apr 2010

Ma Li, Yang Jing, Runesha H Birali, Tanaka Toshiko, Ferrucci Luigi, Bandinelli Stefania, Da Yang

Abstract excerpt

BACKGROUND: Cholesterol concentrations in blood are related to cardiovascular diseases. Recent genome-wide association studies (GWAS) of cholesterol levels identified a number of single-locus effects on total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) levels. Here, we report single-locus and epistasis SNP effects on TC and HDL-C using the Framingham Heart Study (FHS) data. RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epistasis, Genetic

Share to ABCG8 gene

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 20370913
DOI: 10.1186/1471-2350-11-55
PMCID: PMC2867786

Genes

CELSR2
ABCG5
ABCG8
ACAA2
CETP
LCT
LIPG
LMBRD1
LPL
MCM6
OSBPL8
PSRC1
ZDHHC17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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