Article
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
Nature genetics - 1 Jan 2009
Aulchenko Yurii S, Ripatti Samuli, Lindqvist Ida, Boomsma Dorret, Heid Iris M, Pramstaller Peter P, Penninx Brenda W J H, Janssens A Cecile J W, Wilson James F, Spector Tim, Martin Nicholas G, Pedersen Nancy L, Kyvik Kirsten Ohm, Kaprio Jaakko, Hofman Albert, Freimer Nelson B, Jarvelin Marjo-Riitta, Gyllensten Ulf, Campbell Harry, Rudan Igor, Johansson Asa, Marroni Fabio, Hayward Caroline, Vitart Veronique, Jonasson Inger, Pattaro Cristian, Wright Alan, Hastie Nick, Pichler Irene, Hicks Andrew A, Falchi Mario, Willemsen Gonneke, Hottenga Jouke-Jan, de Geus Eco J C, Montgomery Grant W, Whitfield John, Magnusson Patrik, Saharinen Juha, Perola Markus, Silander Kaisa, Isaacs Aaron, Sijbrands Eric J G, Uitterlinden Andre G, Witteman Jacqueline C M, Oostra Ben A, Elliott Paul, Ruokonen Aimo, Sabatti Chiara, Gieger Christian, Meitinger Thomas, Kronenberg Florian, Döring Angela, Wichmann H-Erich, Smit Johannes H, McCarthy Mark I, van Duijn Cornelia M, Peltonen Leena
Abstract excerpt
Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides sampled randomly from 16 population-based cohorts and genotyped using mainly the Illumina...
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