Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

doi:10.1038/ng.75

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Article

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

Nature genetics - 1 Feb 2008

Kathiresan Sekar, Melander Olle, Guiducci Candace, Surti Aarti, Burtt Noël P, Rieder Mark J, Cooper Gregory M, Roos Charlotta, Voight Benjamin F, Havulinna Aki S, Wahlstrand Björn, Hedner Thomas, Corella Dolores, Tai E Shyong, Ordovas Jose M, Berglund Göran, Vartiainen Erkki, Jousilahti Pekka, Hedblad Bo, Taskinen Marja-Riitta, Newton-Cheh Christopher, Salomaa Veikko, Peltonen Leena, Groop Leif, Altshuler David M, Orho-Melander Marju

Abstract excerpt

Blood concentrations of lipoproteins and lipids are heritable risk factors for cardiovascular disease. Using genome-wide association data from three studies (n = 8,816 that included 2,758 individuals from the Diabetes Genetics Initiative specific to the current paper as well as 1,874 individuals from the FUSION study of type 2 diabetes and 4,184 individuals from the SardiNIA study of aging-associated variables...

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Identifiers

PMID: 18193044
DOI: 10.1038/ng.75
PMCID: PMC2682493

Genes

CELSR2
CILP2
GALNT2
PBX4
PSRC1
SORT1
ANGPTL3
MLXIPL
TBL2
TRIB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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