Article
Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2010
Waterworth Dawn M, Ricketts Sally L, Song Kijoung, Chen Li, Zhao Jing Hua, Ripatti Samuli, Aulchenko Yurii S, Zhang Weihua, Yuan Xin, Lim Noha, Luan Jian'an, Ashford Sofie, Wheeler Eleanor, Young Elizabeth H, Hadley David, Thompson John R, Braund Peter S, Johnson Toby, Struchalin Maksim, Surakka Ida, Luben Robert, Khaw Kay-Tee, Rodwell Sheila A, Loos Ruth J F, Boekholdt S Matthijs, Inouye Michael, Deloukas Panagiotis, Elliott Paul, Schlessinger David, Sanna Serena, Scuteri Angelo, Jackson Anne, Mohlke Karen L, Tuomilehto Jaako, Roberts Robert, Stewart Alexandre, Kesäniemi Y Antero, Mahley Robert W, Grundy Scott M, McArdle Wendy, Cardon Lon, Waeber Gérard, Vollenweider Peter, Chambers John C, Boehnke Michael, Abecasis Gonçalo R, Salomaa Veikko, Järvelin Marjo-Riitta, Ruokonen Aimo, Barroso Inês, Epstein Stephen E, Hakonarson Hakon H, Rader Daniel J, Reilly Muredach P, Witteman Jacqueline C M, Hall Alistair S, Samani Nilesh J, Strachan David P, Barter Philip, van Duijn Cornelia M, Kooner Jaspal S, Peltonen Leena, Wareham Nicholas J, McPherson Ruth, Mooser Vincent, Sandhu Manjinder S
Abstract excerpt
OBJECTIVE: Genetic studies might provide new insights into the biological mechanisms underlying lipid metabolism and risk of CAD. We therefore conducted a genome-wide association study to identify novel genetic determinants of low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein...
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