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Article

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study.

BMC medical genetics - 19 Sept 2007

Kathiresan Sekar, Manning Alisa K, Demissie Serkalem, D'Agostino Ralph B, Surti Aarti, Guiducci Candace, Gianniny Lauren, Burtt Nöel P, Melander Olle, Orho-Melander Marju, Arnett Donna K, Peloso Gina M, Ordovas Jose M, Cupples L Adrienne

Abstract excerpt

BACKGROUND: Blood lipid levels including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides (TG) are highly heritable. Genome-wide association is a promising approach to map genetic loci related to these heritable phenotypes. METHODS: In 1087 Framingham Heart Study Offspring cohort participants (mean age 47 years, 52% women), we conducted genome-wide...

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PMID: 17903299
DOI: 10.1186/1471-2350-8-S1-S17
PMCID: PMC1995614

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LPL

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