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Article

Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study.

Atherosclerosis - 1 Nov 2010

Lu Yingchang, Feskens Edith J M, Boer Jolanda M A, Imholz Sandra, Verschuren W M Monique, Wijmenga Cisca, Vaarhorst Anika, Slagboom Eline, Müller Michael, Dollé Martijn E T

Abstract excerpt

BACKGROUND: Plasma total cholesterol (TC) levels are highly genetically determined. Although ample evidence of genetic determination of separate lipoprotein cholesterol levels has been reported, using TC level directly as a phenotype in a relatively large broad-gene based association study has not been reported to date. METHODS AND RESULTS: We genotyped 361 single nucleotide polymorphisms (SNPs) across 243 genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20832063
DOI: 10.1016/j.atherosclerosis.2010.08.053

Genes

ABCA1
ABCG5
APOA5
APOB
APOE
CELSR2
DOCK7
HMGCR
LDLR
NCAN
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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