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Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins

15 Nov 2018

Abstract excerpt

Dyslipidemia represents a strong and independent risk factor for cardiovascular disease. Plasma cholesterol, such as total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C), is the common indicator of diagnosing dyslipidemia. Here based on 382 Chinese twin pairs, we explored the magnitude of genetic impact on TC, HDL-C, LDL-C variation and further...

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PMID: 30498476
DOI: 10.3389/fendo.2018.00677

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