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Article

Impaired gastric gland differentiation in Peutz-Jeghers syndrome.

The American journal of pathology - 1 May 2010

Udd Lina, Katajisto Pekka, Kyyrönen Marika, Ristimäki Ari P, Mäkelä Tomi P

Abstract excerpt

Gastrointestinal hamartomatous polyps in the Peutz-Jeghers cancer predisposition syndrome and its mouse model (Lkb1(+/-)) are presumed to contain all cell types native to the site of their occurrence. This study aimed to explore the pathogenesis of Peutz-Jeghers syndrome polyposis by characterizing cell types and differentiation of the epithelium of gastric polyps and predisposed mucosa. Both antral and fundic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20363912
DOI: 10.2353/ajpath.2010.090519
PMCID: PMC2861111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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