Article

Initial OCT4 engagement with the somatic proteome during reprogramming to iPSC

2020-01-01

Abstract excerpt

Cellular reprogramming to pluripotency can be achieved by using a defined cocktail of transcription factors, converting differentiated somatic cells into induced pluripotent stem cells (iPSCs). These cells behave like embryonic stem cells (ES) and can be used to generate all cell types in the body. OCT4, SOX2, KLF4 and cMYC (OSKM) were the first set of reprogramming factors defined based on both their importance o...

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Literature Corpus work: 456652e8-4035-554c-837a-9b56e7c9e66b
DOI: 10.7488/era/196

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