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Article

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

Cell stem cell - 2 Apr 2010

Pardo Mercedes, Lang Benjamin, Yu Lu, Prosser Haydn, Bradley Allan, Babu M Madan, Choudhary Jyoti

Abstract excerpt

The transcription factor Oct4 is key in embryonic stem cell identity and reprogramming. Insight into its partners should illuminate how the pluripotent state is established and regulated. Here, we identify a considerably expanded set of Oct4-binding proteins in mouse embryonic stem cells. We find that Oct4 associates with a varied set of proteins including regulators of gene expression and modulators of Oct4...

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Source

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Identifiers

PMID: 20362542
DOI: 10.1016/j.stem.2010.03.004
PMCID: PMC2860244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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