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Article

Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.

Antimicrobial agents and chemotherapy - 1 Jun 2010

Chavchich Marina, Gerena Lucia, Peters Jennifer, Chen Nanhua, Cheng Qin, Kyle Dennis E

Abstract excerpt

Artemisinin and its derivatives are the most rapidly acting and efficacious antimalarial drugs currently available. Although resistance to these drugs has not been documented, there is growing concern about the potential for resistance to develop. In this paper we report the selection of parasite resistance to artelinic acid (AL) and artemisinin (QHS) in vitro and the molecular changes that occurred during the...

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Identifiers

PMID: 20350946
DOI: 10.1128/AAC.00947-09
PMCID: PMC2876417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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