Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum.

Antimicrobial agents and chemotherapy - 1 Jan 2012

Tucker Matthew S, Mutka Tina, Sparks Kansas, Patel Janus, Kyle Dennis E

Abstract excerpt

Emergence of artemisinin resistance in Cambodia highlights the importance of characterizing resistance to this class of drugs. Previously, intermediate levels of resistance in Plasmodium falciparum were generated in vitro for artelinic acid (AL) and artemisinin (QHS). Here we expanded on earlier selection efforts to produce levels of clinically relevant concentrations, and the resulting lines were characterized...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Artemisinins
Share to Benzothiazoles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diamines

Share to Inhibitory Concentration 50

Share to Microscopy

Share to Organic Chemicals

Share to Parasitic Sensitivity Tests

Share to Quinolines

Source

Open in PubMed Open full text

Identifiers

PMID: 22083467
DOI: 10.1128/AAC.05540-11
PMCID: PMC3256069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum.PMID 22083467Read ↗

Measuring Growth, Resistance, and Recovery after Artemisinin Treatment of Plasmodium falciparum in a single semi-high-throughput AssaySemantic proximity Read ↗

Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study.Semantic proximity Read ↗

Amodiaquine resistance in Plasmodium berghei is associated with PbCRT His95Pro mutation, loss of chloroquine, artemisinin and primaquine sensitivity, and high transcript levels of key transportersSemantic proximity Read ↗

Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine ResistanceSemantic proximity Read ↗

Artemisinin-resistant Plasmodium falciparum clinical isolates can infect diverse mosquito vectors of Southeast Asia and AfricaSemantic proximity Read ↗

Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterizationSemantic proximity Read ↗

Induction of high tolerance to artemisinin by sub-lethal administration: A new in vitro model of P. falciparum.Semantic proximity Read ↗

Artemisinin-resistant malaria parasites show enhanced transmission to mosquitoes under drug pressureSemantic proximity Read ↗

Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.Semantic proximity Read ↗

Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.Semantic proximity Read ↗

Expanding the Antimalarial Drug Arsenal—Now, But How?Semantic proximity Read ↗

Clinical and In Vitro Resistance of Plasmodium falciparum to Artesunate-Amodiaquine in CambodiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.