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Article

In vitro selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemisinin.

Malaria journal - 22 Jul 2016

Njokah Muturi J, Kang'ethe Joseph N, Kinyua Johnson, Kariuki Daniel, Kimani Francis T

Abstract excerpt

BACKGROUND: Anti-malarial drugs are the major focus in the prevention and treatment of malaria. Artemisinin-based combination therapy (ACT) is the WHO recommended first-line treatment for Plasmodium falciparum malaria across the endemic world. Also ACT is increasingly relied upon in treating Plasmodium vivax malaria where chloroquine is failing. The emergence of artemisinin drug-resistant parasites is a serious...

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Identifiers

PMID: 27449110
DOI: 10.1186/s12936-016-1443-y
PMCID: PMC4957835

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Source receipt: pubmed, retrieved 7 Sept 2026.

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