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Article

LIN28B in constitutional delay of growth and puberty.

The Journal of clinical endocrinology and metabolism - 1 Jun 2010

Tommiska Johanna, Wehkalampi Karoliina, Vaaralahti Kirsi, Laitinen Eeva-Maria, Raivio Taneli, Dunkel Leo

Abstract excerpt

BACKGROUND: Recently variation in LIN28B, a human ortholog of the gene-regulating processing of micro-RNAs (miRNAs) controlling the timing of major developmental events in the nematode Caenorhabditis elegans, was reported to be associated with timing of puberty in humans. In C. elegans, a gain-of-function allele of lin-28 causes a retarded phenotype. OBJECTIVE: The objective of the study was to evaluate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20350940
DOI: 10.1210/jc.2009-2344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

LIN28B in constitutional delay of growth and puberty.PMID 20350940Read ↗

LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious pubertySemantic proximity Read ↗

Genetic variation in LIN28B is associated with the timing of puberty.Semantic proximity Read ↗

LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels.Semantic proximity Read ↗

Association study of LIN28B in girls with precocious puberty.Semantic proximity Read ↗

Sex-specific regulation of weight and puberty by the Lin28/let-7 axisSemantic proximity Read ↗

Genetic determinants of pubertal timing in the general population.Semantic proximity Read ↗

Genetics of pubertal delaySemantic proximity Read ↗

Analysis on cDNA sequence, alternative splicing and polymorphisms associated with timing of puberty of Lin28B gene in goats.Semantic proximity Read ↗

Transient modification of lin28b expression - Permanent effects on zebrafish growth.Semantic proximity Read ↗

Association of LIN28B with adult adiposity-related traits in females.Semantic proximity Read ↗

Absence of Functional <b><i>LIN28B</i></b> Mutations in a Large Cohort of Patients with Idiopathic Central Precocious PubertySemantic proximity Read ↗

Clinical and Genetic Characterization of a Constitutional Delay of Growth and Puberty Cohort.Semantic proximity Read ↗

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