Article
Analysis on cDNA sequence, alternative splicing and polymorphisms associated with timing of puberty of Lin28B gene in goats.
Molecular biology reports - 1 Aug 2013
Cao Guiling, Liu Qiuyue, Chu Mingxing, Di Ran, Fang Li, Feng Tao, Li Ning
Abstract excerpt
Recently, variations in or near Lin28B gene were reported to be associated with timing of human puberty by genome-wide association studies. There have been no reports on that in other mammals. In the present study, a fragment of 5,353 bp of goat Lin28B cDNA, encoding 247 amino acids, was amplified, which contains 744 bp coding region and 4,410 bp 3'-untranslated region (UTR). Two alternative transcripts of...
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