Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Association of LIN28B with adult adiposity-related traits in females.

PloS one - 1 Jan 2012

Leinonen Jaakko T, Surakka Ida, Havulinna Aki S, Kettunen Johannes, Luoto Riitta, Salomaa Veikko, Widén Elisabeth

Abstract excerpt

CONTEXT: Pubertal timing is under strong genetic control and its early onset associates with several adverse health outcomes in adulthood, including obesity, type 2 diabetes and cardiovascular disease. Recent data indicate strong association between pubertal timing and genetic variants near LIN28B, but it is currently unknown whether the gene contributes to the association between puberty and adult disease....

Topics

Adiposity
Adult
Aged
Body Size
DNA-Binding Proteins
Female
Genetic Association Studies
Humans
Male
Metabolome
Middle Aged
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quantitative Trait, Heritable

RNA-Binding Proteins

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23152804
DOI: 10.1371/journal.pone.0048785
PMCID: PMC3496729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of LIN28B with adult adiposity-related traits in females.PMID 23152804Read ↗

Associations between the pubertal timing-related variant in LIN28B and BMI vary across the life course.Semantic proximity Read ↗

Genetic variation in LIN28B is associated with the timing of puberty.Semantic proximity Read ↗

Distinct variants at LIN28B influence growth in height from birth to adulthood.Semantic proximity Read ↗

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.Semantic proximity Read ↗

Genetic determinants of pubertal timing in the general population.Semantic proximity Read ↗

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.Semantic proximity Read ↗

Genetic Regulation of Puberty Timing in HumansSemantic proximity Read ↗

Sex-specific regulation of weight and puberty by the Lin28/let-7 axisSemantic proximity Read ↗

Association study of LIN28B in girls with precocious puberty.Semantic proximity Read ↗

Genetic Relationship Between Menarche and Height in East Asians: Functional Role of LIN28B in Pubertal Timing and Growth.Semantic proximity Read ↗

Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty.Semantic proximity Read ↗

LIN28B affects gene expression at the hypothalamic-pituitary axis and serum testosterone levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.