Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Absence of Functional <b><i>LIN28B</i></b> Mutations in a Large Cohort of Patients with Idiopathic Central Precocious Puberty

1 Jan 2012

Abstract excerpt

AIM: To investigate LIN28B gene variants in children with idiopathic central precocious puberty (CPP). PATIENTS AND METHODS: We studied 178 Brazilian children with CPP (171 girls, 16.8% familial cases). A large multiethnic group (1,599 subjects; Multiethnic Cohort, MEC) was used as control. DNA analysis and biochemical in vitro studies were performed. RESULTS: A heterozygous LIN28B variant, p.H199R, was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Hypothalamic control of reproductive hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nuclear Structure and Function

Source

Identifiers

PMID: 22964795
DOI: 10.1159/000342212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Absence of Functional <b><i>LIN28B</i></b> Mutations in a Large Cohort of Patients with Idiopathic Central Precocious PubertyPMID 22964795Read ↗

Association study of LIN28B in girls with precocious puberty.Semantic proximity Read ↗

Association of genetic polymorphisms around the LIN28B gene and idiopathic central precocious puberty risks among Chinese girls.Semantic proximity Read ↗

LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious pubertySemantic proximity Read ↗

[Recent advances in the genetic etiology of central precocious puberty].Semantic proximity Read ↗

A review of the genetics and epigenetics of central precocious pubertySemantic proximity Read ↗

Molecular analysis of MKRN3 gene in Turkish girls with sporadic and familial idiopathic central precocious puberty.Semantic proximity Read ↗

Association between MKRN3 and LIN28B polymorphisms and precocious puberty.Semantic proximity Read ↗

Genotype–Phenotype Correlations in Central Precocious Puberty Caused by MKRN3 MutationsSemantic proximity Read ↗

Clinical and Genetic Characterization of Familial Central Precocious Puberty.Semantic proximity Read ↗

Genetic variation in LIN28B is associated with the timing of puberty.Semantic proximity Read ↗

Prevalence and clinical characteristics of isolated forms of central precocious puberty: a cohort study at a single academic center.Semantic proximity Read ↗

Analysis on cDNA sequence, alternative splicing and polymorphisms associated with timing of puberty of Lin28B gene in goats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.