Article
Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo.
Journal of cell science - 15 Apr 2010
Lin Meng-Chi, Galletta Brian J, Sept David, Cooper John A
Abstract excerpt
Actin-filament disassembly is crucial for actin-based motility, to control filament network architecture and to regenerate subunits for assembly. Here, we examined the roles of three actin cytoskeletal proteins, coronin, cofilin and Aip1, which have been suggested to combine in various ways to control actin dynamics by promoting or regulating disassembly. We studied their functions during the endocytosis process...
Topics
- Actin Depolymerizing Factors
- Actins
- Alleles
- Green Fluorescent Proteins
- Microfilament Proteins
- Motion
- Phenotype
- Protein Transport
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Time Factors
