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Article

Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis.

The Journal of biological chemistry - 5 Nov 2010

Gandhi Meghal, Jangi Mohini, Goode Bruce L

Abstract excerpt

Coronin is a conserved actin-binding protein that co-functions with ADF/cofilin and Arp2/3 complex to govern cellular actin dynamics. Despite emerging roles for coronin in a range of physiological processes and disease states, a detailed understanding of the molecular interactions of coronin with actin and other binding partners has been lacking. Here, we performed a systematic mutational analysis of surfaces on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20813846
DOI: 10.1074/jbc.M110.171496
PMCID: PMC2966104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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