Article
Genetic evidence for concerted control of actin dynamics in cytokinesis, endocytic traffic, and cell motility by coronin and Aip1.
Cytoskeleton (Hoboken, N.J.) - 1 Jul 2010
Ishikawa-Ankerhold Hellen C, Gerisch Günther, Müller-Taubenberger Annette
Abstract excerpt
Coronin and actin-interacting protein 1 (Aip1) are actin-binding proteins that by different mechanisms inhibit actin polymerization or enhance the disassembly of actin filaments. Cells of Dictyostelium discoideum lacking both proteins are retarded in growth and early development and often fail to proceed to fruiting body formation. Coronin/Aip1-null cells show numerous surface protrusions enriched in filamentous...
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