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Article

Functions of actin-interacting protein 1 (AIP1)/WD repeat protein 1 (WDR1) in actin filament dynamics and cytoskeletal regulation.

Biochemical and biophysical research communications - 25 Nov 2018

Ono Shoichiro

Abstract excerpt

Actin-depolymerizing factor (ADF)/cofilin and actin-interacting protein 1 (AIP1), also known as WD-repeat protein 1 (WDR1), are conserved among eukaryotes and play critical roles in dynamic reorganization of the actin cytoskeleton. AIP1 preferentially promotes disassembly of ADF/cofilin-decorated actin filaments but exhibits minimal effects on bare actin filaments. Therefore, AIP1 has been often considered to be...

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Identifiers

PMID: 29056508
DOI: 10.1016/j.bbrc.2017.10.096
PMCID: PMC5908767

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Source receipt: pubmed, retrieved 7 Sept 2026.

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