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Article

Aip1p dynamics are altered by the R256H mutation in actin.

Journal of visualized experiments : JoVE - 30 Jul 2014

Pierick Alyson R, McKane Melissa, Wen Kuo-Kuang, Bartlett Heather L

Abstract excerpt

Mutations in actin cause a range of human diseases due to specific molecular changes that often alter cytoskeletal function. In this study, imaging of fluorescently tagged proteins using total internal fluorescence (TIRF) microscopy is used to visualize and quantify changes in cytoskeletal dynamics. TIRF microscopy and the use of fluorescent tags also allows for quantification of the changes in cytoskeletal...

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Identifiers

PMID: 25146730
DOI: 10.3791/51551
PMCID: PMC4692351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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