Article
Investigation of reported associations between the 20q13 and 21q22 loci and pediatric-onset Crohn's disease in Canadian children.
The American journal of gastroenterology - 1 Nov 2009
Amre Devendra K, Mack David R, Morgan Kenneth, Fujiwara Mary, Israel David, Deslandres Colette, Seidman Ernest G, Lambrette Phlippe, Costea Irina, Krupoves Alfreda, Fegury Houda, Dong Jinsong, Grimard Guy, Levy Emile
Abstract excerpt
OBJECTIVES: A recent pediatric-focused genome-wide association study has reported novel associations of the 20q13 and 21q22 loci with inflammatory bowel disease (IBD). We aimed to investigate these associations with Crohn's disease (CD) in Canadian children. METHODS: A combined case-control and case-parent design was implemented at three pediatric gastroenterology clinics in Canada. Children less than 20 years of...
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