Article
Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children.
Human genetics - 1 Aug 2010
Amre Devendra K, Mack David R, Morgan Kenneth, Israel David, Deslandres Colette, Seidman Ernest G, Lambrette Phlippe, Costea Irina, Krupoves Alfreda, Fegury Houda, Dong Jinsong, Xhu Zia, Grimard Guy, Levy Emile
Abstract excerpt
A recent pediatric-focused genome-wide association study has implicated three novel susceptibility loci for Crohn' disease (CD).We aimed to investigate whether the three recently reported and other previously reported genes/loci were also associated with CD in Canadian children. A case-control design was implemented at three pediatric gastroenterology clinics in Canada. Children <19 years of age with a confirmed...
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