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Article

HLA and CTLA4 polymorphisms may confer a synergistic risk in the susceptibility to Graves' disease.

Journal of human genetics - 1 May 2010

Takahashi Megumi, Kimura Akinori

Abstract excerpt

Graves' disease (GD) is an autoimmune disease characterized by hyperthyroidism due to the presence of autoantibodies against thyroid-stimulating hormone receptor, which is measured as thyroid-stimulating hormone-binding inhibitory immunoglobulin (TBII). Most of the GD patients are TBII-positive, but TBII is undetectable in a proportion of GD patients. We previously reported the association of HLA-A 02 and -DPB1...

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Source

Identifiers

PMID: 20300120
DOI: 10.1038/jhg.2010.20

Genes

CTLA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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