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Article

Synergistic combined effect between CD40-1C>T and CTLA-4+6230G>A polymorphisms in Graves' disease.

Gene - 10 Aug 2015

Chen Xiaoming, Hu Zhuoqing, Li Wei, Wu Ping, Liu Meilian, Bao Liwen, Wu Meifen, Fang Shuo, Xiong Wei, Chen Manyang, Wu Ge

Abstract excerpt

The aim of this study was to investigate whether a genetic combined effect exists between CD40-1C>T and CTLA-4+6230G>A (CT60) polymorphisms and whether the combined effect renders susceptibility to Graves' disease (GD). We recruited 260 patients with GD and 248 healthy controls. Single nucleotide...

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Source

Identifiers

PMID: 25936345
DOI: 10.1016/j.gene.2015.04.074

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25936345-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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