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Article

Polymorphisms of the genes CTLA4, PTPN22, CD40, and PPARG and their roles in Graves' disease: susceptibility and clinical features.

Endocrine - 1 Jan 2021

Bufalo Natássia Elena, Dos Santos Roberto Bernardo, Rocha Angélica Gomes, Teodoro Larissa, Romaldini João Hamilton, Ward Laura Sterian

Abstract excerpt

PURPOSE: CTLA4, PTPN22, and CD40 are immune-regulatory genes strongly associated with GD, as well as PPARG, but their clinical significance in different populations is still uncertain. METHODS: We genotyped 282 Brazilian GD patients (234 women and 48 men, 39.80 ± 11.69 years old), including 144 patients with GO, and 308 healthy control individuals (246 women and 62 men, 36.86 ± 12.95 years old). RESULTS: A...

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Identifiers

PMID: 32419081
DOI: 10.1007/s12020-020-02337-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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