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Article

Clinical associations of the genetic variants of CTLA-4, Tg, TSHR, PTPN22, PTPN12 and FCRL3 in patients with Graves' disease.

Clinical endocrinology - 1 Feb 2010

Gu Li-qun, Zhu Wei, Zhao Shuang-xia, Zhao Lin, Zhang Min-jia, Cui Bin, Song Huai-dong, Ning Guang, Zhao Yong-ju

Abstract excerpt

OBJECTIVE: Graves' disease (GD) is an organ-specific autoimmune disorder. Both immune-modulating genes and thyroid-specific genes are involved in its genetic pathogenesis. It remains unclear, however, how the interactions of various susceptibility genes contribute to the pathogenesis and clinical severity of the disease. The purpose of this study was to investigate the relationships between GD and single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19438904
DOI: 10.1111/j.1365-2265.2009.03617.x

Genes

PTPN22
FCRL3
TSHR
PTPN12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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