Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of folate and methionine metabolism and PCNSL incidence in a German patient population.

Journal of neuro-oncology - 1 Nov 2010

Kurzwelly Delia, Knop Stefan, Guenther Markus, Loeffler Juergen, Korfel Agnieszka, Thiel Eckhard, Hebart Holger, Simon Matthias, Weller Michael, Linnebank Michael, Herrlinger Ulrich

Abstract excerpt

Functional genetic polymorphisms involved in folate and methionine metabolism play an important role in both DNA synthesis and methylation, and affect the risk of various malignancies including lymphoproliferative disorders such as systemic non-Hodgkin's lymphoma. In a retrospective analysis of 185 immunocompetent patients with primary central nervous system lymphoma (PCNSL) and 212 population controls we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Central Nervous System Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

Share to Germany

Share to Incidence

Share to Lymphoma

Share to Methionine

Share to White People

Source

Identifiers

PMID: 20237949
DOI: 10.1007/s11060-010-0154-4

Genes

MTHFR
CBS
DHFR
MTR
TYMS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of folate and methionine metabolism and PCNSL incidence in a German patient population.PMID 20237949Read ↗

The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma.Semantic proximity Read ↗

Association of MTHFR Polymorphisms With Leukoencephalopathy Risk in Patients With Primary CNS Lymphoma Treated With Methotrexate-Based Regimens.Semantic proximity Read ↗

Association of transcobalamin c. 776C>G with overall survival in patients with primary central nervous system lymphoma.Semantic proximity Read ↗

Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma.Semantic proximity Read ↗

Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes.Semantic proximity Read ↗

Association of genetic variants of methionine metabolism with methotrexate-induced CNS white matter changes in patients with primary CNS lymphomaSemantic proximity Read ↗

Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.Semantic proximity Read ↗

Methionine synthase genetic polymorphism MS A2756G alters susceptibility to follicular but not diffuse large B-cell non-Hodgkin's lymphoma or multiple myeloma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.Semantic proximity Read ↗

Common gene polymorphisms in the metabolic folate and methylation pathway and the risk of acute lymphoblastic leukemia and non-Hodgkin's lymphoma in adults.Semantic proximity Read ↗

Genetic polymorphism of folate and methionine metabolizing enzymes and their susceptibility to malignant lymphoma.Semantic proximity Read ↗

Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.