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Article

Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma.

Haematologica - 1 Feb 2003

Hishida Asahi, Matsuo Keitaro, Hamajima Nobuyuki, Ito Hidemi, Ogura Michinori, Kagami Yoshitoyo, Taji Hirofumi, Morishima Yasuo, Emi Nobuhiko, Tajima Kazuo

Abstract excerpt

BACKGROUND AND OBJECTIVES: Polymorphisms in thymidylate synthase (TS) 28-bp tandem repeats in the promoter region and in cytosolic serine hydroxymethyltransferase (SHMT1 C1420T) have been reported to modulate the risk of adult acute lymphocytic leukemia (ALL). We examined the associations between susceptibility to malignant lymphoma and these polymorphisms. DESIGN AND METHODS: A hospital-based prevalent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12604405

Genes

SHMT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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