Genetic polymorphism of folate and methionine metabolizing enzymes and their susceptibility to malignant lymphoma.

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Article

Genetic polymorphism of folate and methionine metabolizing enzymes and their susceptibility to malignant lymphoma.

Journal of the Egyptian National Cancer Institute - 1 Sept 2005

Habib Emmad Ezzat, Aziz Mona, Kotb Magd

Abstract excerpt

BACKGROUND: Folate and methionine metabolism is involved in DNA synthesis and methylation. Polymorphisms in the genes of folate metabolism enzymes have been associated with some forms of cancer. In the present study, 2 polymorphisms were evaluated for a folate metabolic enzyme, methylene-tetrahydrofolate reductase (MTHFR), and one was evaluated for methionine synthase (MS). The 2 polymorphisms MTHFR 677 C-->T and...

Topics

5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Child
Child, Preschool
DNA Methylation
Female
Folic Acid
Genetic Predisposition to Disease
Genotype
Humans
Lymphoma
Male
Methionine
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 16799656

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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