Article
Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.
British journal of haematology - 1 Feb 2008
Kim Hee Nam, Lee Il-Kwon, Kim Yeo-Kyeoung, Tran Huong Thi Thanh, Yang Deok-Hwan, Lee Je-Jung, Shin Min-Ho, Park Kyeong-Soo, Shin Myung-Geun, Choi Jin-Su, Kim Hyeoung-Joon
Abstract excerpt
Polymorphisms in the genes coding folate-metabolizing enzymes affect the risk of some forms of cancer. We investigated the association between these polymorphisms and non-Hodgkin lymphoma (NHL) risk in a population-based study (583 cases and 1700 controls). The MTHFR 677TT and CT genotypes were associated with reduced risk for NHL [odds ratios (OR) = 0.79; 95% confidence intervals (CI) = 0.65-0.98 for 677CT and...
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