Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.

American journal of hematology - 1 Dec 2004

Matsuo Keitaro, Hamajima Nobuyuki, Suzuki Ritsuro, Ogura Michinori, Kagami Yoshitoyo, Taji Hirofumi, Yasue Tetsuo, Mueller Nancy E, Nakamura Shigeo, Seto Masao, Morishima Yasuo, Tajima Kazuo

Abstract excerpt

Folate and methionine are important nutrients in the "one-carbon" metabolism that is closely associated with DNA synthesis and DNA methylation. Genetic variation in these pathways may change susceptibility to cancer development. We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Logistic Models

Share to Lymphoma

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Source

Identifiers

PMID: 15551285
DOI: 10.1002/ajh.20215

Genes

MTHFR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms and reduced risk of malignant lymphoma.PMID 15551285Read ↗

Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of follicular lymphoma: a meta-analysis.Semantic proximity Read ↗

Association of MTHFR C677T and A1298C polymorphisms with non-Hodgkin lymphoma susceptibility: evidence from a meta-analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms (677C > T and 1298A > C) in Egyptian patients with non-Hodgkin lymphoma.Semantic proximity Read ↗

Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma.Semantic proximity Read ↗

Polymorphisms in methylenetetrahydrofolate reductase gene and risk of non-Hodgkin lymphoma in a multi-ethnic population.Semantic proximity Read ↗

Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.Semantic proximity Read ↗

Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms association with the risk of diffuse large B cell lymphoma: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphism of folate and methionine metabolizing enzymes and their susceptibility to malignant lymphoma.Semantic proximity Read ↗

Risk of non-Hodgkin lymphoma associated with polymorphisms in folate-metabolizing genes.Semantic proximity Read ↗

Methionine synthase A2756G polymorphism and lymphoma risk: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.