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Article

Whole genome survey of copy number variation in the spontaneously hypertensive rat: relationship to quantitative trait loci, gene expression, and blood pressure.

Hypertension (Dallas, Tex. : 1979) - 1 May 2010

Charchar Fadi J, Kaiser Michael, Bingham Andrew J, Fotinatos Nina, Ahmady Fahima, Tomaszewski Maciej, Samani Nilesh J

Abstract excerpt

Copy number variation has emerged recently as an important genetic mechanism leading to phenotypic heterogeneity. The aim of our study was to determine whether copy number variants (CNVs) exist between the spontaneously hypertensive rat (SHR) and its control strain, the Wistar-Kyoto rat, whether these map to quantitative trait loci in the rat and whether CNVs associate with gene expression or blood pressure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20231529
DOI: 10.1161/HYPERTENSIONAHA.109.141663
PMCID: PMC5266550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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