Article
Functional characterisation of the genomes of rat models of human diseases
2014-01-01
Abstract excerpt
Large numbers of inbred laboratory rat strains have been developed in the past 100 years by phenotype-driven selective breeding for the study of a range of disease phenotypes. The spontaneously hypertensive rat (SHR) is the most widely studied animal model of hypertension. The SHR Genome was sequenced with 10.7X coverage, and ~4 million genomic variants between SHR and the BN reference genome were identified. Anal...
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Identifiers and source
- Literature Corpus work
- 2db7bba7-c669-5e53-a9e2-a7a514d1f58f
- DOI
- 10.25560/24545