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Article

Identification of candidate risk gene variations by whole-genome sequence analysis of four rat strains commonly used in inflammation research.

BMC genomics - 21 May 2014

Bäckdahl Liselotte, Ekman Diana, Jagodic Maja, Olsson Tomas, Holmdahl Rikard

Abstract excerpt

BACKGROUND: The DA rat strain is particularly susceptible to the induction of a number of chronic inflammatory diseases, such as models for rheumatoid arthritis and multiple sclerosis. Here we sequenced the genomes of two DA sub-strains and two disease resistant strains, E3 and PVG, previously used together with DA strains in genetically segregating crosses. RESULTS: The data uncovers genomic variations, such as...

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Identifiers

PMID: 24885425
DOI: 10.1186/1471-2164-15-391
PMCID: PMC4041999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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