Article
Significant gene content variation characterizes the genomes of inbred mouse strains.
Genome research - 1 Dec 2007
Cutler Gene, Marshall Lisa A, Chin Ni, Baribault Helene, Kassner Paul D
Abstract excerpt
The contribution to genetic diversity of genomic segmental copy number variations (CNVs) is less well understood than that of single-nucleotide polymorphisms (SNPs). While less frequent than SNPs, CNVs have greater potential to affect phenotype. In this study, we have performed the most comprehensive survey to date of CNVs in mice, analyzing the genomes of 42 Mouse Phenome Consortium priority strains. This...
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