Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy number variation influences gene expression and metabolic traits in mice.

Human molecular genetics - 1 Nov 2009

Orozco Luz D, Cokus Shawn J, Ghazalpour Anatole, Ingram-Drake Leslie, Wang Susanna, van Nas Atila, Che Nam, Araujo Jesus A, Pellegrini Matteo, Lusis Aldons J

Abstract excerpt

Copy number variants (CNVs) are genomic segments which are duplicated or deleted among different individuals. CNVs have been implicated in both Mendelian and complex traits, including immune and behavioral disorders, but the study of the mechanisms by which CNVs influence gene expression and clinical phenotypes in humans is complicated by the limited access to tissues and by population heterogeneity. We now...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Basal Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Comparative Genomic Hybridization

Share to Gene Dosage

Share to Mice, Inbred C3H

Share to Mice, Inbred Strains

Share to Muscles

Source

Open in PubMed Open full text

Identifiers

PMID: 19648292
DOI: 10.1093/hmg/ddp360
PMCID: PMC2758141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy number variation influences gene expression and metabolic traits in mice.PMID 19648292Read ↗

Significant gene content variation characterizes the genomes of inbred mouse strains.Semantic proximity Read ↗

The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells.Semantic proximity Read ↗

Genomic copy number variation in Mus musculus.Semantic proximity Read ↗

Segmental copy number variation shapes tissue transcriptomes.Semantic proximity Read ↗

Copy number variants, diseases and gene expression.Semantic proximity Read ↗

AI Analysis of a Copy Number Variant Database Identifies a Genetic Factor for a Murine Model of the Metabolic SyndromeSemantic proximity Read ↗

The impact of human copy number variation on gene expression.Semantic proximity Read ↗

Copy number variation and susceptibility to complex traits.Semantic proximity Read ↗

Human genes involved in copy number variation: mechanisms of origin, functional effects and implications for disease.Semantic proximity Read ↗

A high-resolution map of segmental DNA copy number variation in the mouse genome.Semantic proximity Read ↗

Genomic copy number and expression variation within the C57BL/6J inbred mouse strain.Semantic proximity Read ↗

Recurrent DNA copy number variation in the laboratory mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.