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Article

Azithromycin alters macrophage phenotype and pulmonary compartmentalization during lung infection with Pseudomonas.

Antimicrobial agents and chemotherapy - 1 Jun 2010

Feola David J, Garvy Beth A, Cory Theodore J, Birket Susan E, Hoy Heather, Hayes Don, Murphy Brian S

Abstract excerpt

Infection with mucoid strains of Pseudomonas aeruginosa in chronic inflammatory diseases of the airway is difficult to eradicate and can cause excessive inflammation. The roles of alternatively activated and regulatory subsets of macrophages in this pathophysiological process are not well characterized. We previously demonstrated that azithromycin induces an alternatively activated macrophage-like phenotype in...

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Identifiers

PMID: 20231397
DOI: 10.1128/AAC.01424-09
PMCID: PMC2876369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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