Article
Characterization of macrophage activation states in patients with cystic fibrosis.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Sept 2010
Murphy Brian S, Bush Heather M, Sundareshan Vidya, Davis Christina, Hagadone Jennifer, Cory Theodore J, Hoy Heather, Hayes Don, Anstead Michael I, Feola David J
Abstract excerpt
BACKGROUND: Chronic airway inflammation characterizes patients with cystic fibrosis (CF). The role of alternative macrophage activation in this disease course is unknown. OBJECTIVE: We evaluated markers of alternative and classical macrophage activation in the lungs of patients with CF and evaluated these characteristics in the context of Pseudomonas aeruginosa (PA) infection, immunomodulatory drug therapy and...
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