Article
Lack of association between the rs6920220 (G/A) polymorphism of the 6q23 region and biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 May 2010
Palomino-Morales Rogelio, Torres Orlando, Vazquez-Rodriguez Tomas R, Castañeda Santos, Morado Inmaculada C, Miranda-Filloy Jose A, Amigo-Diaz Encarnacion, Callejas-Rubio Jose L, Fernandez-Gutierrez Benjamin, Martin Javier, Gonzalez-Gay Miguel A
Abstract excerpt
OBJECTIVE: Recently, 2 independent studies have identified an association between several single-nucleotide polymorphisms (SNP) located in the 6q23 chromosomal region and rheumatoid arthritis (RA). Like RA, giant cell arteritis (GCA) is also a complex polygenic disease in which more than 1 genetic locus is likely to contribute to disease susceptibility and clinical expression. We analyzed the involvement of the...
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