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Article

Lack of association between IRF5 gene polymorphisms and biopsy-proven giant cell arteritis.

The Journal of rheumatology - 1 Jan 2010

Torres Orlando, Palomino-Morales Rogelio, Vazquez-Rodriguez Tomas R, Castañeda Santos, Morado Inmaculada C, Miranda-Filloy Jose A, Valero Fernando, Callejas-Rubio Jose L, Fernandez-Gutierrez Benjamin, Martin Javier, Gonzalez-Gay Miguel A

Abstract excerpt

OBJECTIVE: Interferon (IFN) regulatory factors (IRF) are transcriptional mediators of IFN-induced signaling pathways and are involved in immune response. We have analyzed for the first time the association of 2 IRF5 gene variants in the susceptibility to giant cell arteritis (GCA). METHODS: Two hundred twenty patients with biopsy-proven GCA and 520 matched controls were assessed. DNA from patients and controls...

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Source

Identifiers

PMID: 19918036
DOI: 10.3899/jrheum.090744

Genes

GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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