Article
Influence of IL2RA rs2104286 polymorphism in the risk of biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 Nov 2010
Rodríguez-Rodríguez Luis, Castañeda Santos, Vázquez-Rodríguez Tomás R, Morado Inmaculada C, Marí-Alfonso Beatriz, Gómez-Vaquero Carmen, Miranda-Filloy José A, Ortego-Centeno Norberto, Narvaez Javier, Blanco Ricardo, Fernández-Gutiérrez Benjamín, Martín Javier, González-Gay Miguel A
Abstract excerpt
OBJECTIVE: To assess the influence of the IL2RA rs2104286 A>G polymorphism on susceptibility to and clinical spectrum of manifestations of biopsy-proven giant cell arteritis (GCA). METHODS: Our study included 318 patients with biopsy-proven GCA. DNA from patients and healthy controls was obtained from peripheral blood. Samples were genotyped for the IL2RA rs2104286 A>G polymorphism using a predesigned TaqMan...
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