Article
Lack of association between TRAF1/C5 gene polymorphisms and biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 Jan 2010
Torres Orlando, Palomino-Morales Rogelio, Vazquez-Rodriguez Tomas R, Castañeda Santos, Morado Inmaculada C, Miranda-Filloy Jose A, Ortego-Centeno Norberto, Gonzalez-Alvaro Isidoro, Fernandez-Gutierrez Benjamin, Martin Javier, Gonzalez-Gay Miguel A
Abstract excerpt
OBJECTIVE: A novel association with a 100-kb region on chromosome 9 that contains the tumor necrosis factor receptor-associated factor 1 (TRAF1) and C5 genes has been observed in some autoimmune rheumatic diseases, in particular in rheumatoid arthritis. We analyzed the influence of 2 single-nucleotide polymorphisms (SNP) from the TRAF1/C5 region in susceptibility to giant cell arteritis (GCA). METHODS: We...
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